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A study on the photodynamic therapy of photosensitizercoated magnetic nanoparticles

R.-M. ION1,2, D.-V. BREZOI1,*

Affiliation

  1. Valahia University, Targoviste, 130024, Romania
  2. ICECHIM, Bucharest, 060021, Romania

Abstract

One of the important points in the use of magnetic nanoparticles for biomedical applications is the encapsulation of the magnetic material, in order to make it biocompatible, producing a bio-ferrofluid. In this paper, ferrimagnetic particles of Fe3O4 were nanometrically synthesized. In order to coat a photosensitizer on the magnetic particles, TSPP was choosed and introduced into the ferrofluid suspension containing magnetite and the adsorption reaction was conducted at 60, 70, and 80 oC. Analytical investigations (UV-Vis, TEM, XRD, TGA) argued the TSPP encapsulated into Fe3O4..

Keywords

Magnetic nanoparticles, Ferrofluids, TSPP, Photosensitizers.

Submitted at: Nov. 2, 2006
Accepted at: April 15, 2007

Citation

R.-M. ION, D.-V. BREZOI, A study on the photodynamic therapy of photosensitizercoated magnetic nanoparticles, Journal of Optoelectronics and Advanced Materials Vol. 9, Iss. 4, pp. 936-939 (2007)