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Bioactivity evaluation of new silver doped bone cement for prosthetic surgery

S. CAVALU1,* , V. SIMON2, C. ALBON2, C. HOZAN1

Affiliation

  1. University of Oradea, Faculty of Medicine and Pharmacy, P-ta 1 Decembrie10, Oradea 410068 Romania
  2. Babes-Bolyai University, Faculty of Physics, Cluj-Napoca 400084, Romania

Abstract

Due to the broad antimicrobial spectrum of silver, the composites used as bone substitutes or for coating metallic implants can be doped with silver. Polymer-ceramic composites are widely applied in orthopaedics due to their biocompatibility and ability to support bone growth (osteoconductivity) and also due to bioactivity implied by self-assembling of a hydroxyapatite type layer on their surface. This in vitro study is focussed on surface microstructure changes in simulated body fluid and on antibacterial silver release from two different types of biocomposites doped with silver. SEM microscopy and ATR-FTIR spectroscopy were employed in order to evaluate the properties of the surface layer after immersion in simulated body fluid..

Keywords

Silver, Antimicrobial, Simulated body fluid, SEM, ATR FTIR.

Submitted at: Nov. 15, 2006
Accepted at: March 15, 2007

Citation

S. CAVALU, V. SIMON, C. ALBON, C. HOZAN, Bioactivity evaluation of new silver doped bone cement for prosthetic surgery, Journal of Optoelectronics and Advanced Materials Vol. 9, Iss. 3, pp. 690-693 (2007)