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Electrospun polymers for controlled release of drugs, vaccine delivery, and system-on-fibers

A. VASEASHTA1,* , I. STAMATIN2

Affiliation

  1. Nanomaterials Processing & Characterization Laboratories, Department of Physics & Graduate, Program in Physical Sciences Marshall University, Huntington, WV 25575-2570, USA
  2. Nanosciences& Alternative Energy Sources Research Center, University of Bucharest, Faculty of Physics, Romania, Bucharest- Magurele, MG-38, Romania

Abstract

This investigation presents a comprehensive overview of our ongoing efforts and future directions of research using inorganic and organic nano-biomaterials. One of the key objectives of our research is to develop sensors that can readily detect gases, and chemical and biological molecules for applications ranging from contamination to environmental pollution. Among several processes used to fabricate chem.-bio sensors, we are currently using an electrospinning process to develop several composite fibers with application in chemical, biological, and gas sensing application. As an extension, we have investigated several biodegradable polymers for possible construction of excipient therapeutic templates. There are a number of natural and synthetic biodegradable polymers that are being used and proposed for targeted vaccine and drug delivery, and for both soft and hard tissue repair. Such fibers-by-design address many issues relating to the fundamental challenge in the synthesis of fibers for System-on-Fiber (SOF), and will have tremendous application in network appliances, personal entertainment, and global security and defense..

Keywords

System-on-Fiber, Biodegradable, Electrospinning, Smart Textile, Chem.-bio sensors, Active Nanostructures.

Submitted at: Nov. 14, 2006
Accepted at: June 15, 2007

Citation

A. VASEASHTA, I. STAMATIN, Electrospun polymers for controlled release of drugs, vaccine delivery, and system-on-fibers, Journal of Optoelectronics and Advanced Materials Vol. 9, Iss. 6, pp. 1606-1613 (2007)