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Fabrication of bioactive implants through biomimetic deposition of hydrox yapatite onto the micro arc o xidation created porous TiO 2 coating

JUN FENG LI1, QUAN MING ZHAO2,* , XIAO FENG GU2, ZHONG TANG LIU3, LI CHENG2

Affiliation

  1. Department of Material Science and Engineering, Chengdu University of Technology, Chengdu City , 610059 , Sichuan Province , P.R. China
  2. Department of Orthopedic Surgery, Wuxi People ’s Hospital, Nanjing Medical University, Wuxi City 214023, Jiangsu Province, P.R. China;
  3. Department of Orthoped ic Surgery, Changhai Hospital, The Second Military Medical University, Shanghai 200433, China

Abstract

Titanium (Ti) and its alloys are considered as candidate materials for bone implants . To improve the bioactivity of the implants, surface modifications are ne cessary . This study reports a new method to deposit hydroxyapatite (HA) HA). It us es biomimetic deposition in simulated body fluid (SBF) within the TiO 2 coating created by micro arc oxidation (MAO) treatment of a Ti plate. The morphology, chemical and phase co mposition of the coatings were examined by scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS) and X ray diffraction (XRD). The MTT assay was then used to determine the cell proliferation efficiency on different coatings. In vitro cell ular assays showed that the incorporation of HA significantly improved the osteoblastic activity. In conclusion, we developed a simple, flexible and reliable method to grow the TiO 2 /HA composite coatings which opens up a new avenue toward designing Ti bas ed medical implants..

Keywords

: Titanium implants ; H ydroxyapatite; Micro arc oxidation; Biomimetic deposition.

Submitted at: Dec. 1, 2014
Accepted at: May 7, 2015

Citation

JUN FENG LI, QUAN MING ZHAO, XIAO FENG GU, ZHONG TANG LIU, LI CHENG, Fabrication of bioactive implants through biomimetic deposition of hydrox yapatite onto the micro arc o xidation created porous TiO 2 coating, Journal of Optoelectronics and Advanced Materials Vol. 17, Iss. 5-6, pp. 660-664 (2015)