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Membrane bending elasticity of human erythrocyte ghosts

V. VITKOVA1,* , V. DOLTCHINKOVAa2, M. D. MITOV1, I. BIVAS1

Affiliation

  1. Institute of Solid State Physics, Bulgarian Academy of Sciences, 72 Tzarigradsko Chaussee Blvd., 1784 Sofia, Bulgaria
  2. Department of Biophysics and Radiobiology, Faculty of Biology, Sofia University “St. Kliment Ohridski”, 8 Dragan Tsankov Blvd., 1164 Sofia, Bulgaria

Abstract

An experimental study of the membrane bending elasticity of human erythrocyte ghosts is presented. The bending modulus was determined by analysing the shape fluctuations of quasi-spherical ghosts. The obtained results show that: i) the bending elasticity of erythrocyte ghosts is equal to several times the Boltzmann factor and ii) it belongs to the lower part of the existing interval of experimental values, reported in the literature for the bending elasticity of red blood cell membranes..

Keywords

Erythrocyte ghost, Bending elasticity, Thermal fluctuation analysis.

Submitted at: Nov. 1, 2006
Accepted at: Feb. 15, 2007

Citation

V. VITKOVA, V. DOLTCHINKOVAa, M. D. MITOV, I. BIVAS, Membrane bending elasticity of human erythrocyte ghosts, Journal of Optoelectronics and Advanced Materials Vol. 9, Iss. 2, pp. 431-434 (2007)