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Nanoporous glass in Na2O-B2O3-SiO2 oxidic system, for potential biomedical applications

C. MAZILU1,* , E. ROTIU1, L. IONESCU1, D. RADU2, A. DINISCHIOTU3

Affiliation

  1. National Glass Institute, Theodor Pallady Blv., no.47, Sector 3, Bucharest, Romania
  2. Politehnica University of Bucharest, Faculty of Applied Chemistry and Materials Science, Department of Science and Engineering of Oxide Materials and Nanomaterials, Romania
  3. University of Bucharest, Splaiul Independentei Str., no. 91-95, Bucharest, Romania

Abstract

The adsorption phenomenon of organic molecules in micro and nanoporous solids has been known for a long time but it has raised a considerable interest in the last years when different types of porous materials that are used in enzymatic catalysis, chemical biosensors, chromatographic columns or drug support, have been investigated. Because of the advantages that porous glass presents compared to other types of organic or inorganic porous materials, high mechanical resistance, thermal stability, rigid structure immune to biological and chemical degradation, etc., the glasses with a better controlled porosity are researched and used more and more. In this paper, we report on the preparation of a nanoporous glass with the pores' diameter between 10-300 nm, with interconnected pores, fabricated on the base of microphase separation in an alkaline borosilicate glass. The glass composition was chosen in the Na2O-B2O3-SiO2 system. The obtained materials have been characterized physico-chemically (chemical and thermal analysis, X-ray diffraction), microstructurally (atomic force microscopy) and from the point of view of the bioproperties that present interest (pH dynamics, noncitotoxicity, cellular proliferation, adsorption and enzymatic activity)..

Keywords

Na2O-B2O3-SiO2 glass, Nanoporous, Biomedical applications.

Submitted at: Dec. 13, 2006
Accepted at: July 15, 2007

Citation

C. MAZILU, E. ROTIU, L. IONESCU, D. RADU, A. DINISCHIOTU, Nanoporous glass in Na2O-B2O3-SiO2 oxidic system, for potential biomedical applications, Journal of Optoelectronics and Advanced Materials Vol. 9, Iss. 7, pp. 2036-2040 (2007)