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Nanosized magnetite for biomedical applications

I. NEDKOV1,*

Affiliation

  1. Institute of Electronics, Bulgarian Academy of Sciences, 72 Tzarigradsko Chaussee, 1784 Sofia, Bulgaria

Abstract

Nanosized magnetite particles can be potentially used in the targeted delivery of therapeutic agents in vivo, in the hyperthermic treatment of tumours, in magnetic resonance imaging (MRI) as contrast agents and in the bio magnetic separation of bio-molecules. An understanding of the motion, heating and visualization of these nanoparticles in physiological systems in vitro and in vivo is required to tailor these nanoparticles for some of these applications. These applications are based on the biocompatibility of magnetite and on the nanoparticle’s magnetic characteristics, namely the superparamagnetic (SPM) behaviour and the high saturation magnetization (magnetite exhibits one of the largest magnetic moments among oxides). The very small crystal size and the surface effects have a strong influence on the magnetic behaviour of these materials. The work sets out to clarify the impact of oxidation on the magnetite particle characteristics and presents new data about some bio-magnetic applications for SPM magnetite..

Keywords

Magnetite, Nanoparticles, Surface effects, Hyperthermia.

Submitted at: Nov. 1, 2006
Accepted at: Jan. 15, 2007

Citation

I. NEDKOV, Nanosized magnetite for biomedical applications, Journal of Optoelectronics and Advanced Materials Vol. 9, Iss. 1, pp. 24-29 (2007)