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Study of a polymer-clay nanocomposite material interaction with a VERO cell line for cytotoxic evaluation

M. MICULESCU1,* , G. MOŢIU2, M. RĂDUŢ2, D. DONESCU3, M. C. COROBEA3

Affiliation

  1. University "Politehnica" of Bucharest, 202 Splaiul Independentei, 060042, Bucharest, Romania
  2. Centre for Research and Production of Biologicals and Drugs for Veterinary Use - ROMVAC Company, Centurii Road, No.7, Voluntari, Ilfov County, Romania
  3. National Research an Development Institute for Chemistry and Petrochemistry - ICECHIM, 202 Splaiul Independentei, 060021, Bucharest, Romania

Abstract

A new polymer-clay nanocomposite material based on poly(vinyl acetate), poly(vinyl pyrrolidone) and a layered silicate (sodium montmorillonite) as nanofiller, is deposed in different concentration on a VERO cell line in order to evaluate the cytotoxic behaviour. The polymeric system without nanofiller was also investigated. For both investigated materials the nanocomposite and the unfilled polymeric system the results showed no sign of cytotoxic effect on the cells. The materials interaction with the cell media showed different morphologies depending on the dilution level..

Keywords

Poly(vinyl acetate), Poly(vinyl pyrrolidone), Layered silicate, Vero cell line, Cytotoxicity.

Submitted at: March 23, 2007
Accepted at: Nov. 16, 2007

Citation

M. MICULESCU, G. MOŢIU, M. RĂDUŢ, D. DONESCU, M. C. COROBEA, Study of a polymer-clay nanocomposite material interaction with a VERO cell line for cytotoxic evaluation, Journal of Optoelectronics and Advanced Materials Vol. 9, Iss. 11, pp. 3364-3367 (2007)