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Theoretical investigation of sensitivity enhancement by using gold nanoparticles in a sensing layer and 2D-nanomaterials in SPR biosensor

SAEED GHORBANI1,* , MOJTABA SADEGHI1,* , ZAHRA ADELPOUR1

Affiliation

  1. Department of Electrical Engineering, Shiraz Branch, Islamic Azad University, Shiraz, Iran

Abstract

The all-optical biosensor based on Surface Plasmon Resonance (SPR) with improved sensitivity is introduced which exploits theoretical analysis and simulation of biomaterial detection in liquids. A five-layer Kretschmann configuration is considered with emphasis on nanocomposite structure of sensing layer along with extra two-dimensional (2D) layer. Sensing layer consists of gold nanoparticles with biomaterial sample shell. Moreover, different types of 2D material (graphene, Black Phosphorous (BP) and tungsten disulfide (WS2)) with variable thickness are considered beneath the sensing layer. Comprehensive simulations based on Maxwell-Garnett theory are done to fully investigate the nanocomposite physical characteristics effect, thickness and the type of 2D material layer on biosensor performance. It is concluded that in the case of 5nm core radius, 5nm shell thickness and 0.1 filling factor, the improved sensitivity value of 260.385 (°⁄RIU) is achievable if a 24nm layer of WS2 2D material is added beneath the sensing layer. The proposed biosensor has a high sensitivity being capable of real-time monitoring the samples. By considering the special characteristics of the proposed biosensor, this biosensor can be considered as a good candidate for biomaterial sample detection in liquids..

Keywords

Optical biosensor, Surface plasmon resonance, Sensitivity, Core-shell nanostructure, Nonocomposite, Maxwell-Garnett theory.

Submitted at: May 12, 2021
Accepted at: April 8, 2022

Citation

SAEED GHORBANI, MOJTABA SADEGHI, ZAHRA ADELPOUR, Theoretical investigation of sensitivity enhancement by using gold nanoparticles in a sensing layer and 2D-nanomaterials in SPR biosensor, Journal of Optoelectronics and Advanced Materials Vol. 24, Iss. 3-4, pp. 114-124 (2022)